SUDEP – more attention to the heart? A narrative review on molecular autopsy in epilepsy
نویسندگان
چکیده
Sudden unexpected death in epilepsy (SUDEP) has been identified as one of the most prevalent causes mortality epilepsy, and SUDEP consequently become an important topic research. The appear multifactorial, including epilepsy-induced cardiac arrest. Current understanding autopsy negative sudden unexplained (SUD) general population its relation to arrhythmic syndrome (SADS) could shed some light SUDEP. Mutual attention findings cardiology are discussed here. We performed a narrative review on SUDEP, molecular/genetic this population. A proposal extended terminology for classification is recent issues related molecular genetics. might be step forward research protocols tool better
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15 صفحه اول[Sudden unexpected death in epilepsy: SUDEP].
Sudden unexpected death in epilepsy (SUDEP) is the most important direct epilepsy-related cause of death. Patients with refractory epilepsy are at especially high risk of SUDEP. SUDEP occurs predominantly at night and unwitnessed, and can best be regarded as a fatal tonic-clonic seizure. While its pathophysiology is incompletely understood, SUDEP is most probably triggered by a number of predis...
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ژورنال
عنوان ژورنال: Seizure-european Journal of Epilepsy
سال: 2021
ISSN: ['1532-2688', '1059-1311']
DOI: https://doi.org/10.1016/j.seizure.2021.03.010